Abstract: The sliding friction and wear properties of the vacuum-quenched Cr12MoV die steel under different load and rotating speed were studied under dry friction conditions.The friction coefficient, the amount of wear, the microstructure and the wear mark morphology of the sample were analyzed by the friction tester, the electronic balance, OM and SEM. The results show that, with the increase of the load, the coefficient of friction of the specimen increases at first and then decreases.The increase of wear is caused by the adhesive tear on the friction surface and the falling off of carbide hard particles.With the increase of rotating speed, the friction coefficient of the sample increases at first and then decreases. The reason for the increase of wear is caused by the continuous formation and spalling of the oxide film on the friction surface.Under low load, the wear mode of the sample is abrasive wear, and with the increase of load, the wear mode becomes a mixed form of abrasive wear and adhesive wear. At low rotating speed, the wear mode of the sample is abrasive wear. With the increase of rotating speed, the wear mode of the sample changes to the peeling wear caused by the continuous formation and shedding of the oxide film at the friction interface.