Abstract: The effects of different contents of rare earth oxide Y₂O₃ on the microstructure, friction and wear and high temperature oxidation resistance of laser cladding coating on the surface of titanium alloy TC4 were investigated. A 2 kW fiber laser was used to prepare Ni60A-50% Cr₃C₂ containing 0.2%, 0.5%, 0.8%, 1.0%, 2.0%, and 3.0% Y₂O₃ powders. The microstructure and phase composition of the coating on the surface of TC4 were analyze by SEM, XRD and EDS. The hardness of the coating was studied by microhardness tester. The friction and wear tests were carried out by MMG-500 three-body abrasion tester, and the high temperature oxidation test was carried out by WS-G150 smart muffle furnace. Results show that, when the addition amount of Y₂O₃ is 1.0%, the microstructure and properties of the coating is better than other addition amounts of Y₂O₃. The coating has no defects,with good forming. The coating generates high hardness carbides and intermetallic compounds. The microstructure of the heat affected zone of the matrix is acicular martensite, the microstructure of the bonding zone of the coating layer is plane crystal and columnar crystal, and the microstructure of the middle and the upper surface of the coating layer is short cell crystal and dendritic cryctal. The maximum microhardness of the coating is 1604HV0.2, which is about 4.6 times than that of the substrate. The friction coefficient of the coating is basically stable at about 0.33, which is less than the friction coefficient of the TC4 substrate 0.5-0.7. The abrasion resistance of the coating significantly improves compared with the substrate. The oxidized weight gain of the coating after oxidation at a constant temperature of 850 ℃ for 100h is 5.11 mg·cm^-2, which is about 20% of the TC4 substrate's oxidized weight gain of 25.8mg· cm^-2. The high temperature oxidation resistance significantly improves. The appropriate addition of rare earth Y₂O₃ can effectively improve the microstructure and properties of TC4 laser cladding layer.