Abstract: The laser welding tests of sinusoidal scanning path and non-scanning path were carried out for 5 mm thick plates of 316LN stainless steel and Inconel 718 superalloy dissimilar materials.The influence of welding process parameters on the weld quality was studied, and the microstructure, microhardness and tensile properties of laser welding joints were studied.The results show that the laser welding without scanning path is easier to achieve stable welding and get good weld forming than the scanning welding with sinusoidal path.The laser welded joint with sinusoidal path has a large number of pores in the lower part of the weld, and there are no pores in the laser welded joint without scanning path.With the increase of welding speed, the surface forming of the laser welding joint without scanning path becomes better.When the welding speed is 1.8 m/min, the widths of weld seam's upper and lower surface become narrow, and there is no undercut, splash defects.The weld zone presents columnar dendrite structures that are perpendicular to the fusion line and growing to the weld center, and M₂₃C₆ type carbide is precipitated in the weld seam, which improves the weld strength.The microhardness of the welded joint shows a gradually decreasing trend from Inconel718 base material to weld seam and then to 316LN base material.The fracture positions of welded joints are all located on 316LN base material far away from the welding seam.The tensile strength can reach 650 MPa at room temperature and the fracture mode of joints is ductile fracture.