Abstract: The breakthrough in material science has provided more possibilities for the development of biomedical.Ti/HA is favored in the field of biomedical materials due to its excellent mechanical properties, biocompatibility and activity, but they still have many problems.The interface problems and improvement methods of Ti/HA were mainly introduced.The application of several Ti-Sn alloys in biomedical materials was introduced and Ti-Sn/hydroxyapatite composites were presented.