Abstract: Taking high-strength aluminum alloy powder as raw material, the static and fatigue properties of transverse and longitudinal printed samples were studied which produced by selecting laser melting printing with determining the process and post-processing parameters. The results show that the tensile yield strength and ultimate strength in both directions are higher than 500 MPa, and the fracture mode is ductile way according to the cross section analysis after stretching. The strength and plasticity of the printed parts decrease due to oxide inclusion and non-fusion. The mean value of K_IC in both directions is close and the dispersion of all data is small. In the crack growth rate test, the stable growth zone can be clearly identified, and the Paris model is used to fit the results. Furthermore, the fatigue limit under different conditions is determined by high cycle fatigue test at room temperature. The raw materials, additive manufacturing process and engineering performance of high strength aluminum alloy were studied comprehensively.