Abstract: N08367/Q345R super austenitic stainless steel clad plates were prepared by vacuum hot rolling cladding（VRC）. The effects of different cooling rates on the microstructure and properties of N08367/Q345R clad plates after rolling were studied. The results show that the average shear strength of the clad plates under three different cooling rates is more than 456 MPa, far beyond the national standard, and the shear strength of the clad plates under water cooling process is the highest,reaching 466 MPa. With the increase of cooling rate, the diffusion distance of Fe, Cr, Ni and Mo elements decreases, and there are obvious decarburizing layer and carburizing layer near the interface. The maximum values of microhardness is located in the carburizing zone and the minimum value is located in the decarburizing zone.