Abstract: Titanium-aluminum intermetallic compounds have the characteristics of low density,high melting point,high specific strength,high temperature oxidation resistance and corrosion resistance. As a new generation of aerospace,aircraft blade and automotive turbine materials,they have attracted widespread attention in recent years. The properties and applications of titanium-aluminum intermetallic compounds were introduced,the research progress of powder metallurgy,ingot metallurgy,aluminothermic reduction and molten salt methods was summarized,the advantages and disadvantages of each method were analyzed and compared,and the future development direction of titanium-aluminum intermetallic compounds was prospected.