Abstract: According to the different performance requirements of stent, crown bridge, and local removable denture in the prosthesis, according to the industry standard of dental additive manufacturing metal materials, the prosthesis with excellent strength and plastic matching was produced. TC4 titanium alloy was fabricated by 3D printing laser selective melting（SLM）technology, after annealing, the effect of annealing temperature on the microstructure and mechanical properties was studied.Subsequently, the microstructure, fracture morphology and performance were analyzed by tensile test, scanning electron microscope, EDS, XRD test and other analytical methods, and the conclusion was drawn.SLM forming dental TC4 alloy original state because of the high heat-cold temperature difference makes the β phase too late to transform into（α+β） phase,resulting in a large number of acicular α’ martensite phase.After annealing at 550 ℃×1 h/FC（with furnace cooling）, there is still a large amount of α’ phase. When the annealing temperature further increases, the α’ martensite phase begin to decompose into（α+β） phase, and the microstructure changes from the Widmanstatten structure to the Basketweave structure.When the annealing temperature is 950 ℃, the volume of the α and β phases gradually increases, the yield strength decreases, and the elongation after fracture increases. After comprehensive comparison, the samples anneal at 850 ℃×1 h/FC has the best yield strength of 1066 MPa, tensile strength of 1128MPa, and elongation after fracture of 10.6%, the mechanical properties are best and fully meet the standard of metal materials for dental restoration.