Abstract: In order to improve the service life of 304 stainless steel parts in chemical pipeline network, the high entropy alloy coating was prepared on the surface of 304 stainless steel substrate by laser cladding technology; the physical phase composition, micro-morphology and elemental distribution of the cladding layer were analyzed by X-ray diffractometer, scanning electron microscope and energy spectrometer respectively, and the hardness distribution, tribological and electrochemical properties were investigated by microhardness tester, tribological wear tester and electrochemical workstation respectively. The results show that the optimum process parameters for the forming quality of the fused cladding layer are: laser power of 600 W, powder feeding rate of 7.5 g·min^-1 and scanning speed of 2.0 mm·s^-1. The friction coefficient of the substrate is about 0.76, which is higher than that of the fused cladding layer of 0.46; the wear amount of the fused cladding layer is 4.25 mg, which is about 61% of that of the substrate of 2.75 mg, which indicate that the solid solution phase can enhance the coating's deformation resistance. After electrochemical corrosion test, the self-corrosion current density of the fused cladding layer is about 1.21×10^-7 A·cm^-2, compared with the substrate to reduce 9.2×10^-8 A·cm^-2, the self-corrosion potential of the fused cladding layer is about -0.64 V, compared with the substrate compared with the increase of 0.11 V, the fused cladding layer melting arc radius is significantly larger than the substrate; in the medium frequency region (100-102), the impedance of fused cladding layer is larger than the substrate, indicating a significant reduction in the corrosion tendency of the coating. This indicates that the corrosion tendency of the coating is significantly reduced. The results show that CoCrFe- NiTi high-entropy alloy coating can significantly improve the tribological stability and electrochemical properties of the coating.